Mast cell tumours (MCTs) are one of the most common skin cancers in dogs. They are notorious for variability — some are entirely benign and excised cleanly, others are aggressive and metastatic. Outwardly they often look like a simple lump, sometimes hairless, sometimes red or itchy, sometimes changing in size.

Breeds with higher incidence: Boxer, Bulldog, Labrador, Golden Retriever, Pug, Boston Terrier, Pit Bull. The "Boxer with a lump" stereotype is grounded in reality.

The right approach to any new lump: fine-needle aspirate first. Mast cells are highly distinctive on cytology, so a quick in-clinic aspirate (often the same day as discovery) can confirm or rule out MCT before any decision about surgery.

Treatment depends on grading. Low-grade MCTs are usually cured by surgical removal with wide margins. Higher-grade tumours may need chemotherapy, radiation, or targeted therapy. Localised cases often have good outcomes; metastatic cases require oncology specialist input.

Bottom line: never "watch and see" a new lump on a Boxer or similar predisposed breed. Aspirate first.