Canine parvovirus is one of the most feared infectious diseases in puppies. The virus attacks rapidly dividing cells — particularly the intestinal lining and bone marrow — causing severe bloody diarrhoea, vomiting, dehydration, immune suppression, and often death.

Most cases occur in puppies between 6 weeks and 6 months — after maternal antibodies wane but before the full vaccination series is complete. This is why vets stress that unvaccinated puppies should not visit public dog spaces.

Signs come on suddenly: profound lethargy, vomiting, watery or bloody diarrhoea, refusal of food, sometimes fever. Without treatment, death usually follows in 48–72 hours. With aggressive treatment (hospitalisation, IV fluids, anti-nausea, antibiotics, plasma, sometimes monoclonal antibody therapy), survival rates are 70–90%.

Prevention is straightforward: puppy vaccinations at 6–8, 10–12, and 14–16 weeks; titer check or booster at 1 year; periodic boosters thereafter. Until 2 weeks after the final puppy vaccine, avoid public dog spaces.

Parvovirus is extremely environmentally hardy — surviving months on surfaces. Outbreaks recur in places where vaccination compliance drops.